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Ack1 inhibitor 37
CAS No. 1026493-77-5
Ack1 inhibitor 37( —— )
Catalog No. M10126 CAS No. 1026493-77-5
Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 372 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameAck1 inhibitor 37
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NoteResearch use only, not for human use.
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Brief DescriptionAck1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM.
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DescriptionAck1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM); demonstrates cell IC50 of 10 nM in cellular autophosphorylation assays, displays excellent ACK1 cellular inhibition, good kinase selectivity, and a suitable in vitro metabolic profile.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetAck1 (TNK2)
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RecptorAck1 (TNK2)
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Research Area——
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Indication——
Chemical Information
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CAS Number1026493-77-5
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Formula Weight517.71
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Molecular FormulaC28H31N5OS2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CCN(C1)CCOC2=CC=C(C=C2)C3=C(C4=C(N3)N=CN=C4NCC5SCCS5)C6=CC=CC=C6
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Chemical NameN-((1,3-dithiolan-2-yl)methyl)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiao X, et al. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6212-7.
2. Mahajan K, et al. Cancer Lett. 2013 Sep 28;338(2):185-92.
molnova catalog
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